Progress in Erectile Dysfunction Therapy via Drug Delivery System

Abstract

A man’s aptitude to acquire and continue an erection is frequently equated with masculinity and virility and is able to greatly influence men’s confidence. The sexual healthiness is a significant determinant of the worth of life. ED as the inability to have or sustain a penile erection long enough to have momentous sexual intercourse with a partner. As per literature, the millions of men populations are suffering from ED and there is an extreme need to overcome the ED. The various natural traditional herbs, synthetic chemical entities potentials are preferred to treat ED. The present review discusses ED therapy including drug selection, application site, choice of formulation, etc. Moreover, this review updates the various pharmaceutical formulation such as liposomes, nano-ethosomes, transfersomes, microemulsion, SNEDDS, solid dispersion, penetrosomes, SLNs and NLCs, etc. development in ED therapy via the oral route, topical and nasal route, etc, which are helpful for researchers to develop new nanocarriers based formulations.