Stilbenoids from the stem of Diospyros collinsae, the first evidence for the production of stilbene derivatives in Ebenaceous plants

Buntita Bumroong, Witchuda Thanakijcharoenpath

Abstract


Two stilbenoids, diptoindonesin D (1) and diptoindonesin G (2), were isolated from the stem of Diospyros collinsae Craib (Ebenaceae), together with four triterpenoids, namely friedelin, lupeol, betulin and betulinic acid. Their structures were determined by spectroscopic analysis. Diptoindonesin G (2) exhibited cytotoxic activity against NCI-H187 cells and antimalarial activity against Plasmodium falciparum. The isolation of 1 and 2 provided the first evidence for the production of stilbene derivatives in plants of the family Ebenaceae. 


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