Study of antioxidant, antimicrobial, tyrosinase inhibitory, alcohol dehydrogenase, and acetaldehyde dehydrogenase activity of roasted Dendropanax morbifera LEV. leaves with different ethanol concentrations

masaya nakamura, Ra Jong-Hwan, Kim Ju-Sung

Abstract


Introduction: The history of Dendropanax morbifera LEV., which is indigenous plant in Korea, is quit old and simultaneously, known for locals as remedy of various diseases such as migraine and inflammation. The aim of this study is evaluating the antioxidant, antimicrobial, and biological activity (tyrosinase inhibitory, alcohol dehydrogenase (ADH), and acetaldehyde dehydrogenase (ALDH) activity) of roasted Dendropanax morbifera LEV. leaves with different ethanol concentrations. Method: The roasted and ethanol extract (0%, 20%, 40%, 60%, 80%, and 100%) of Dendropanax morbifera LEV. leaves were examined through assays of 2,2-azino-bis-(3-ethylbenzothiazothiazoline-6-sulfornic acid) (ABTS), 1,1-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, total phenol and flavonoid content, reducing power, tyrosinase inhibitory, ADH and ALDH activity, and minimum inhibitory concentration (MIC). Result and Conclusion: In most assays, significant activity was observed in the 100% ethanol extract, and the degree of activity decreased as the ethanol concentration decreased. However, the results for the tyrosinase inhibitory activity were different. The 80% and 60% ethanol extracts exhibited the highest l-tyrosine and l-3,4-dihydroxyphenylalanine (l-DOPA) activities, respectively. Simultaneously, the roasting process probably takes part in the regeneration and distraction of phenolic compounds, possibly other compounds, contributing to the higher activity of Dendropanax morbifera LEV. leaves


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References


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